The Difference in the Effectiveness of Propolis and Triamcinolone Acetonide in Traumatic Ulcer Healing in Mucosa of the Oral Cavity

Alioes, Yustini and Hamdan, Hamdan and SY, Elmatris (2019) The Difference in the Effectiveness of Propolis and Triamcinolone Acetonide in Traumatic Ulcer Healing in Mucosa of the Oral Cavity. In: CONFERENCE PROCEEDING 3rd INTERNATIONAL CONFERENCE ON SECURITY IN FOOD, RENEWABLE RESOURCES, AND NATURAL MEDICINES 2019 (SFRN 2019). pusat penelitian dan pengabdian pada masyarakat Politeknik Pertanian Negeri Kupang. ISBN 9786025126284

Text The Difference in the Effectiveness of Propolis and Triamcinolone Acetonide in Traumatic Ulcer Healing in Mucosa of the Oral Cavity.pdf Download (493kB)

Abstract

A traumatic ulcer is a lesion on the oral cavity caused by trauma. These ulcers usually painful and often require topical drugs and systemic treatments are effective. Propolis is one of the herbal remedy products that have been widely used in the treatment and prevention of various diseases, such as treating wounds after mayor surgery and inhibit the growth of fungi, such as Candida. This research is using the pre-test – post-test control group research design, done in the animal house, at the biochemistry department, faculty of medicine, Universitas Andalas using 20 mice as samples. On the first day, 20 mice are given 5% H2O2 liquid on the bottom lip of the labial mucosa to stimulate the onset of ulcer. The next day, the initial traumatic ulcer is formed, and the size is measured. After the initial ulcer is formed, the size of the ulcer is measured twice a day (morning and evening) at control group I (which is treated with propolis) and control group II (treated with triamcinolone acetonide) performed for ten days. An average of traumatic ulcer healing was seven days with propolis application and 6.9 days with the application of triamcinolone acetonide. The results of the statistical analysis using Independent T-test demonstrated the value of p = 0,874 (p < 0.05). It was concluded that the activity of triamcinolone acetonide is better than propolis in healing the traumatic ulcer.

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